What is THC-B? And Effect, Potency, Legality.

It might be difficult to stay up-to-date with the most recent cannabis-related research, given the growing cannabinoid market and the regular discovery of new cannabinoids by scientists. THC-B, for instance, was only recently found small amount from plants. As its amazing potency became known, more products are developing and entering the market.

But what exactly is THC-B? What are the effect and advantages? Learn it from here!

What Is THC-B?

THC-B, a short form of delta-9 tetrahydrocannabutol, is a cannabinoid that is similar to THC. If you don’t know, THC is the phytocannabinoid that is most prevalent in marijuana and is mostly in charge of its psychoactive effects.

The THC-B cannabinoid was uncovered in 2019 by a group of Italian researchers bred by the Italian military together with THCP, THCH, and other novel cannabinoids that had never been identified from cannabis strains FM2.

What THC-B Effects And Potency?

The way THC interacts with the endocannabinoid system in the brain, scientists believe that THC-B works primarily by influencing the CB1 and CB2 receptors.

CB1 and CB2 Receptors
CB1 and CB2 Receptors

Because THC-B is a homologue of THC, this means it has a similar molecular structure and works as Delta 9-THC.

But its alkyl side chain has one less carbon than Delta 9 THC, so Delta 9-THCb is also called Delta 9-THC-C4. The shorter four-carbon alkyl side chain makes it bind to the CB1 receptor with a stronger affinity. This higher affinity means that it binds the CB1 receptor more effectively and is 13 times more bioactivity than Delta 9-THC.

On the other hand, the butyl phytocannabinoid THC-B binds to CB1 differently than THC. They didn’t fit this channel, but from another water-repelling pocket fit into. Thus in practice experience may vary.

THC vs THC-B molecular
Delta 9-THC vs Delta 9-THCb molecular

THC-B Benefits And Side Effect

As THCB is new to the cannabis world, the discovery of its benefits and effects is just beginning.

THC-B could be a potential sleep aid, although we’re not sure if it has the same intoxicating properties as THC. However, so far, no evidence of this effect in humans has been found.

THC-B has only been validated in one study, hardly scratching the surface of all its possible applications. Given THC-B’s recent discovery, next to nothing is known regarding its potential uses or benefits.

Moreover, following the discovery of this cannabinoid, studies on mice  produced promising results similar to THC’s impact on humans. THC-B may act in the same way as THC in terms of anti-inflammatory and pain-relieving properties, according to a preliminary study.

Is THC-B Legal?

In Europe

THC-B is not an isomer or stereoisomer of THC – Tetrahydrocannabinol, it is not scheduled as controlled substance on EU Green List.

If the THC-B raw material is a derivative of natural cannabis and is not completely synthesized in the laboratory, it is likely to be outside the scope of the European “New Drug Law” but it is not clear, such as the NPSG law in Germany.


The Farm Bill of 2018 made hemp and hemp-derived products legal under federal law in the United States. If they are screened and shown to have a THC content of 0.3% or less, hemp products may be marketed legally across the nation under this law. THC-B is permitted by federal law, but things are more complicated.

Regardless of the federal government’s stance, a few states have outlawed or severely regulated intoxicating hemp derivatives.

Will THC-B Show Up on a Drug Test?

As said earlier, THC-B hasn’t been the subject of much research, so it isn’t easy to clarify whether the substance will result in a failed drug test. Nevertheless, generally speaking, you can presume that a cannabinoid will cause you to fail a drug test if its name contains the letters “THC.”

By identifying the THC-COOH enzyme, that digests all THC-based cannabinoids, standard drug tests determine if a person has used illicit drugs. THC-B is more powerful than delta 9. Hence it seems reasonable that it will screen positive for drugs more frequently than THC. You should avoid THC-B for several weeks if a you expect a drug screen test. 

Is THC-B Safe?

The lack of evidence suggests that THC-B users must take prudence. Its safety profile is probably comparable to that of the more well-known cannabinoid THC, because its molecular makeup is comparable to delta 9.

Although there aren’t any known long-term negative consequences of THC-B, consuming too much can have unpleasant side effects such as dizziness, dry mouth, or drowsiness.

It’s crucial to start THC-B slowly so that your body has time to acclimatize and respond. Even if you only use THC, taking too much THC-B may not be a great thing because of its great potency. If you dose too low, you can always consume more; however, once you hit your threshold, there is no turning back. 

Is There Any THC-B Product To Try?

If you’re interested in giving it a try, start with a low dose. The 420 E-Liquid presented to you by KANNASTAR contains 90MG THC-B, which is suitable for traditional electronic cigarettes. Since the amount of vapor and frequency of use of this device is higher than general cannabis vaporizer, that’s why you should not underestimate it.

THCB E-Liquid
THC-B E-Liquid
THC-B Vape Pen
THC-B Vape Pen Starter Kits

Final Thoughts

THC-B, albeit still young, can dominate the industry in the coming years. THC-B is a fantastic choice for individuals seeking a “kick” that is distinct from any other because it has similar medical benefits to delta 9—including deep sleep, anti-inflammatory properties, and pain control, an immense strength.

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