What is CBC?

What is CBC?

You’ve heard of cannabinoids, notably the two most well-known, THC and CBD. But you’ve probably never heard of cannabichromene or CBC. CBC is among the most prominent cannabinoids studied in medicinal studies, identified more than half a century ago.

Granting that it does not receive as much recognition, the effects of CBC are pretty intriguing. CBC opens a world of therapeutic benefits from treating pain and inflammation to diminishing acne and other skin-related conditions.

Are you interested in learning about CBC? Here is everything you should know.

About CBC

THC and CBD are both derived from cannabigerolic acid (CBGA), where CBC comes from. to put it another way, CBGA is a parent of three main active ingredients:

· Tetrahydrocannabinolic acid (THCA)

· Cannabidiolic acid (CBDA)

· Cannabichromenic acid (CBCA)

After a specific process, the CBGA plant chemical directs the breakdown result into any of the three channels. CBGA, upon exposure to high temperatures or ultraviolet rays, changes it from cannabichromene carboxylic acid (CBCA) and ultimately to CBC.

How Does CBC Work?

CBC is non-intoxicating like CBD, and therefore it does not create the same psychoactive effects as THC. Since it interacts weakly with CB1 cannabinoid receptors in the central nervous system, it is non-intoxicating. However, CBC binds to various receptors in the body, including

· TRPV1 (vanilloid receptor 1)

· TRPA1 (transient receptor potential ankyrin 1)

These receptors are generally considered to be contributing factors for pain sensitivity.

When CBC stimulates those channels, your body starts to produce higher quantities of the body’s endogenous endocannabinoids, such as anandamide. Such working of CBC is quite comparable to CBD as it also boosts the endocannabinoids production instead of interacting with them directly.

Although CBC has distinct effects, scientists believe it works synergistically with other compounds, a phenomenon described as the entourage effect. Although the effectiveness of THC and CBD functioning synergistically is well-known, it is unclear if additional cannabinoids exhibit entourage effects.

What are the Possible Health Benefits of CBC?

The alleged advantages of CBC entail more repercussions. A couple of health problems that cannabichromene can help with are listed below.


Cannabichromene’s interplay with the body’s endocannabinoid, anandamide, renders it a potent cancer fighter. CBC also cuts the anandamide accumulation, permitting it to stay in the bloodstream for prolonged periods.

In a recent survey wherein tumor progression was induced in rats, Cannabinoids efficiently reduce chronic inflammation and tumor formation. Given that anandamide has been found to inhibit breast cancer in study subjects, CBC and other cannabinoids may in future be used as a tumor suppressor.

A 2006 research investigating cannabinoids apart from THC and their probable implications on cancer initially identified CBC as a potent anti-cancer weapon. Although THC is well-known for its anti-tumour capabilities in various cancers, its robust psychoactive features can make it challenging to combine with chemotherapy. According to a study, CBC is the second-most active cannabinoid at suppressing the formation of malignant cancerous cells.

Pain and Inflammation

Cannabichromene has been demonstrated to reduce pain and inflammation in osteoarthritis caused by collagen. Cannabinoids such as CBC have a unique function for inflammatory conditions, unlike non-steroidal anti-inflammatory medications. They don’t possess the same damaging consequences. In a novel animal experiment, CBC with THC showed anti-inflammatory activity. These two cannabinoids, when combined, provided a considerably higher action on inflammatory response than either cannabinoid alone.

Brain Cells

CBC showed a favorable response on neuronal stem progenitor cells (NSPCs), a cell necessary for proper cognitive function, in a 2013 mouse research. When NSPCs were exposed to CBC, they became highly active, promising since NSPCs convert into astroglial cells, the most critical in regulating central nervous system health. The astroglial cells have a variety of roles, notably neurotransmitter distribution and oxidative cellular defense. Many of the problems that produce neurodegenerative disorders and brain disorders such as Alzheimer’s disease, oxidative stress, inflammatory processes, and toxic effects are counteracted by astrocytes.


A scientific group that previously demonstrated CBD’s effectiveness on acne looked into the benefits of additional cannabinoids, particularly CBC. Furthermore, CBC has been proved to be an effective acne blocker. Acne is a skin condition marked by excessive sebum deposition and irritation of the sebaceous glands. CBC was discovered to have potent anti-inflammatory actions and suppress high-fat accumulation in the sebaceous glands. Arachidonic acid (AA), which is required for lipid synthesis, was likewise decreased by CBC. More research is necessary. However, CBC could potentially be a very effective anti-acne medication.


In another classic case of the entourage effect, CBC tends to function in tandem with THC and CBD to provide a triumvirate of antidepressant effects.

The Takeaway?

CBC is not a new cannabinoid but it is not much studied as THC and CBD. However, the medicinal potential of CBC is significant. Furthermore, additional investigation is needed to assess its efficacy on its own and in grouping with other compounds for an entourage effect.

Kannastar’s hemp full spctrum has been detected to contain varying levels of CBC, and the company will launch CBC-based Hemp products in the near future.

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